USP 800 Compliance expands on USP 797 and describes requirements for handling hazardous drugs, facility controls, and procedures for deactivating, decontaminating and cleaning.
Wipe Sampling
Wipe sampling is the act of wiping areas of interest with a swab which is later tested in a lab. The test can determine if certain hazardous drugs are present and is designed to prevent contamination. According to USP 800, wipe sampling should be done a minimum of twice a year.
Critical Areas to Sample
Interior of the C-PEC
Pass-through chambers
Staging or work areas
Floors and dispensing areas
Outside HD buffer room
Patient administration areas
What Drugs to Test For
Cyclophosphamide
Ifosfamide
Methotrexate
Fluorouracil
Platinum Containing Drugs
Who Enforces USP 800 Compliance?
USP standards were created by The United States Pharmacopeial Convention along with the FDA. The guidelines are enforceable at the state level. Most commonly, the State Board of Pharmacy performs inspections.